Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 19/20 | 1.00 |
| ▸ | MAOA | P21397 | 6/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19994596 | 1.00 | MAOB (1.00) | MAOBMAOA | |
| SCHEMBL20015286 | 0.83 | MAOB (1.00) | MAOBMAOA | |
| SCHEMBL20015297 | 0.83 | MAOB (1.00) | MAOBMAOA | |
| SCHEMBL20015282 | 0.83 | MAOB (1.00) | MAOBMAOA | |
| SCHEMBL20015284 | 0.83 | MAOB (1.00) | MAOBMAOA | |
| SCHEMBL20015287 | 0.83 | MAOB (1.00) | MAOBMAOA | |
| SCHEMBL20015296 | 0.82 | MAOB (1.00) | MAOBMAOA | |
| SCHEMBL20015288 | 0.80 | MAOB (1.00) | MAOBMAOA | |
| SCHEMBL20015295 | 0.80 | MAOB (1.00) | MAOBMAOA | |
| SCHEMBL20015293 | 0.80 | MAOB (1.00) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3426634-A1 | DISUBTITUTED AZETIDINES, PYRROLIDINES, PIPERIDINES AND AZEPANES AS INHIBITORS OF MONOAMINE OXIDASE B FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | University of Ljubljana (SI) | 2019-01-16 | — | — | EP | disclosed |
| WO-2018055096-A1 | DISUBTITUTED AZETIDINES, PYRROLIDINES, PIPERIDINES AND AZEPANES AS INHIBITORS OF MONOAMINE OXIDASE B FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | UNIVERSITY OF LJUBLJANA (SI) | 2018-03-29 | — | — | WO | disclosed |