Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 4/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.45 |
| ▸ | BID | P55957 | 4/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.44 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.44 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | CTSG | P08311 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8625728 | 0.97 | IAPP (0.48) | IAPPALOX5PTGS2HMGB1BID | |
| SCHEMBL1640151 | 0.97 | IAPP (0.48) | IAPPALOX5PTGS2HMGB1BID | |
| Zinc Ion SCHEMBL10584384 | 0.94 | BID (0.52) | IAPPALOX5PTGS2BIDMCL1 | |
| Zinc Ion SCHEMBL7084049 | 0.94 | BID (0.52) | IAPPALOX5PTGS2BIDMCL1 | |
| Zinc Ion SCHEMBL10581371 | 0.94 | BID (0.52) | IAPPALOX5PTGS2BIDMCL1 | |
| SCHEMBL9790326 | 0.91 | BID (0.52) | IAPPALOX5PTGS2BIDMCL1 | |
| SCHEMBL31372911 | 0.91 | BID (0.52) | IAPPALOX5PTGS2BIDMCL1 | |
| SCHEMBL11169533 | 0.91 | BID (0.52) | IAPPALOX5PTGS2BIDMCL1 | |
| SCHEMBL3517528 | 0.91 | BID (0.52) | IAPPALOX5PTGS2BIDMCL1 | |
| SCHEMBL11125907 | 0.91 | BID (0.52) | IAPPALOX5PTGS2BIDMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10286825-A | — | — | None | — | — | JP | disclosed |
| US-20110151255-A1 | NANOFIBER AND PREPARATION METHOD THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2011-06-23 | — | — | US | disclosed |
| JP-H10286825-A | METHOD FOR CONVEYING AND/OR MELT-KNEADING POWDER | MITSUBISHI CHEM CORP | 1998-10-27 | — | — | JP | disclosed |