SCHEMBL19998010

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19998011	0.98	EGFR (0.44)	EGFRKDM4EALDH1A1HPGDHTT
	SCHEMBL19997999	0.90	EGFR (0.38)	EGFRKDM4EALDH1A1HPGDHTT
	SCHEMBL19998000	0.88	TOP1 (0.46)	EGFRKDM4EALDH1A1HPGDHTT
	SCHEMBL12691069	0.86	EGFR (0.49)	EGFRKDM4EALDH1A1HPGDHTT
	SCHEMBL18926320	0.85	EGFR (0.43)	EGFRKDM4EALDH1A1HPGDHTT
	SCHEMBL17426601	0.84	EGFR (0.49)	EGFRKDM4EALDH1A1HPGDHTT
	SCHEMBL12690869	0.83	EGFR (0.44)	EGFRKDM4EALDH1A1HPGDHTT
	SCHEMBL19986145	0.83	EGFR (0.42)	EGFRKDM4EALDH1A1HPGDHTT
	SCHEMBL19986028	0.83	EGFR (0.42)	EGFRKDM4EALDH1A1HPGDHTT
	SCHEMBL26239605	0.83	KDM4E (0.43)	EGFRKDM4EALDH1A1HPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.