Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 19/20 | 0.66 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.66 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.66 |
| ▸ | MGLL | Q99685 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15002430 | 0.93 | PARP1 (0.69) | PARP1PARP2PARP3MGLL | |
| SCHEMBL15002410 | 0.92 | PARP1 (0.66) | PARP1PARP2PARP3MGLL | |
| SCHEMBL15002563 | 0.90 | PARP1 (0.69) | PARP1PARP2PARP3MGLL | |
| SCHEMBL15002406 | 0.89 | PARP1 (0.72) | PARP1PARP2PARP3MGLL | |
| SCHEMBL15002561 | 0.88 | PARP1 (0.64) | PARP1PARP2PARP3MGLL | |
| SCHEMBL16215126 | 0.87 | PARP1 (0.66) | PARP1PARP2PARP3MGLL | |
| SCHEMBL15002407 | 0.85 | PARP1 (0.72) | PARP1PARP2PARP3MGLL | |
| SCHEMBL15002408 | 0.84 | PARP1 (0.73) | PARP1PARP2PARP3MGLL | |
| SCHEMBL15001747 | 0.83 | PARP1 (0.81) | PARP1 | |
| SCHEMBL17356392 | 0.81 | PARP1 (0.52) | PARP1PARP2PARP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2799435-B1 | POLY (ADP-RIBOSE) POLYMERASE INHIBITOR | CHENGDU DIAO PHARMACEUTICAL GROUP CO LTD (CN) | 2018-03-28 | — | — | EP | disclosed |