Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | STAT1 | P42224 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3536462 | 0.88 | TSHR (0.33) | TSHRNPC1RAB9AALOX5LMNA | |
| SCHEMBL13314785 | 0.88 | TSHR (0.33) | TSHRNPC1RAB9AALOX5LMNA | |
| SCHEMBL17044541 | 0.76 | MAPT (0.44) | TSHRNPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL3536434 | 0.74 | TSHR (0.32) | TSHRNPC1RAB9ALMNAPARP1 | |
| SCHEMBL13314783 | 0.74 | TSHR (0.32) | TSHRNPC1RAB9ALMNAPARP1 | |
| SCHEMBL13314788 | 0.72 | TSHR (0.31) | TSHRPARP1 | |
| SCHEMBL3542567 | 0.72 | TSHR (0.31) | TSHRPARP1 | |
| SCHEMBL17044543 | 0.71 | MAPT (0.40) | NPC1RAB9AMAPTALDH1A1POLB | |
| SCHEMBL3537408 | 0.68 | TSHR (0.35) | TSHRNPC1RAB9ALMNAMAPT | |
| SCHEMBL13314818 | 0.63 | TSHR (0.32) | TSHRNPC1RAB9ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018058109-A1 | COMPOSITIONS AND METHODS FOR TREATING METABOLIC DISORDERS | NUSIRT SCIENCES, INC. (US) | 2018-03-29 | — | — | WO | disclosed |