Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 4/20 | 0.49 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.38 |
| ▸ | NEU4 | Q8WWR8 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 6/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23081491 | 0.89 | SMPD1 (0.57) | SMPD1ARCYP1A2CYP2C19HRH4 | |
| SCHEMBL616778 | 0.86 | SMPD1 (0.67) | SMPD1HRH4HRH3GBA1 | |
| SCHEMBL12392028 | 0.85 | HRH4 (0.51) | SMPD1HRH4HRH3IDO1IDO2 | |
| SCHEMBL16264805 | 0.85 | AR (0.42) | SMPD1ARCYP1A2CYP2C19HRH4 | |
| SCHEMBL10065573 | 0.80 | NR1H4 (0.42) | SMPD1ARCYP1A2CYP2C19HRH4 | |
| SCHEMBL16263166 | 0.79 | AR (0.41) | SMPD1ARCYP1A2CYP2C19HRH4 | |
| SCHEMBL18625956 | 0.77 | NEU4 (0.37) | SMPD1ARCYP1A2CYP2C19NEU4 | |
| SCHEMBL4224866 | 0.77 | GBA1 (0.47) | GBA1 | |
| SCHEMBL14037186 | 0.76 | NEU4 (0.40) | SMPD1ARCYP1A2CYP2C19HRH4 | |
| SCHEMBL616557 | 0.76 | NR1H4 (0.39) | SMPD1ARCYP1A2CYP2C19NEU4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2999707-B1 | TYLOSIN DERIVATIVES AND METHOD FOR PREPARATION THEREOF | BAYER ANIMAL HEALTH GMBH (DE) | 2018-03-28 | — | — | EP | disclosed |