Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21401950 | 0.78 | TSHR (0.36) | TSHR | |
| SCHEMBL21307646 | 0.75 | — | — | |
| SCHEMBL12443370 | 0.74 | — | — | |
| SCHEMBL20001885 | 0.70 | — | — | |
| SCHEMBL7166749 | 0.68 | IDO1 (0.33) | TSHR | |
| SCHEMBL1011191 | 0.68 | — | — | |
| SCHEMBL20839289 | 0.68 | IDO1 (0.33) | TSHR | |
| SCHEMBL8313321 | 0.68 | — | — | |
| SCHEMBL128287 | 0.67 | TSHR (0.31) | TSHR | |
| SCHEMBL20002640 | 0.63 | TSHR (0.30) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018057973-A1 | COMPOUNDS AND METHODS FOR IDO AND TDO MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC. (US) | 2018-03-29 | — | — | WO | disclosed |