Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.37 |
| ▸ | SAT1 | P21673 | 2/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16789969 | 0.98 | CYP2C19 (0.52) | CYP2C19CYP1A2KDM1AMEN1GLA | |
| SCHEMBL3608460 | 0.91 | CYP2C19 (0.50) | CYP2C19CYP1A2KDM1AMEN1GLA | |
| SCHEMBL24764606 | 0.82 | CYP2C19 (0.50) | CYP2C19CYP1A2KDM1AMEN1GLA | |
| SCHEMBL14044481 | 0.81 | TSHR (0.55) | CYP2C19CYP1A2KDM1AMEN1GLA | |
| SCHEMBL15966144 | 0.81 | TSHR (0.55) | CYP2C19CYP1A2KDM1AMEN1GLA | |
| SCHEMBL15966128 | 0.81 | TSHR (0.55) | CYP2C19CYP1A2KDM1AMEN1GLA | |
| SCHEMBL15966125 | 0.81 | TSHR (0.55) | CYP2C19CYP1A2KDM1AMEN1GLA | |
| SCHEMBL15966140 | 0.81 | TSHR (0.55) | CYP2C19CYP1A2KDM1AMEN1GLA | |
| SCHEMBL14163249 | 0.81 | CHRM2 (0.64) | CYP2C19CYP1A2KDM1AMEN1GLA | |
| SCHEMBL40907 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4166553-A1 | ALKENYL PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Hongyun Biotech Co., Ltd. (CN) | 2023-04-19 | — | — | EP | disclosed |
| WO-2018057834-A1 | COMBINATORY TREATMENT STRATEGIES OF CANCER BASED ON RNA POLYMERASE I INHIBITION | THE JOHNS HOPKINS UNIVERSITY (US) | 2018-03-29 | — | — | WO | disclosed |