Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.46 |
| ▸ | EML4 | Q9HC35 | 2/20 | 0.40 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.40 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20004099 | 0.86 | ALK (0.63) | ALKEML4SRPK2SRPK1KDR | |
| SCHEMBL25446835 | 0.77 | ALK (0.58) | ALK | |
| SCHEMBL20366593 | 0.77 | ALK (0.58) | ALK | |
| SCHEMBL20004738 | 0.76 | ALK (0.75) | ALKEML4SRPK2SRPK1KDR | |
| SCHEMBL20004124 | 0.75 | ALK (0.56) | ALKEML4SRPK2SRPK1KDR | |
| SCHEMBL7802442 | 0.75 | ALK (0.58) | ALKEML4SRPK2SRPK1KDR | |
| SCHEMBL24676341 | 0.75 | ALK (0.54) | ALKKDRKIT | |
| SCHEMBL20366581 | 0.74 | ALK (0.54) | ALKEML4SRPK2SRPK1KDR | |
| SCHEMBL29940684 | 0.74 | ALK (0.59) | ALKEML4SRPK2SRPK1 | |
| SCHEMBL27087519 | 0.74 | ALK (0.59) | ALKEML4SRPK2SRPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |