Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL898087 | 0.88 | ALK (0.79) | ALK | |
| SCHEMBL25446835 | 0.86 | ALK (0.58) | ALK | |
| SCHEMBL20366593 | 0.86 | ALK (0.58) | ALK | |
| SCHEMBL7804494 | 0.80 | ALK (0.50) | ALK | |
| SCHEMBL1755915 | 0.79 | ALK (0.58) | ALK | |
| SCHEMBL16775619 | 0.79 | ALK (0.65) | ALK | |
| SCHEMBL897440 | 0.78 | ALK (0.65) | ALK | |
| SCHEMBL20004748 | 0.78 | ALK (0.82) | ALK | |
| SCHEMBL898262 | 0.78 | ALK (0.71) | ALK | |
| SCHEMBL7800549 | 0.77 | ALK (0.55) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |