Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20366644 | 1.00 | ALK (0.61) | ALK | |
| SCHEMBL898122 | 0.83 | ALK (0.69) | ALK | |
| SCHEMBL20004563 | 0.82 | ALK (0.71) | ALK | |
| SCHEMBL20004774 | 0.79 | ALK (0.43) | ALK | |
| SCHEMBL21443235 | 0.79 | ALK (0.43) | ALK | |
| SCHEMBL21443225 | 0.76 | ALK (0.81) | ALK | |
| SCHEMBL29962453 | 0.76 | ALK (0.78) | ALK | |
| SCHEMBL898277 | 0.76 | ALK (0.78) | ALK | |
| SCHEMBL898504 | 0.76 | ALK (1.00) | ALK | |
| SCHEMBL1703892 | 0.76 | ALK (0.80) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |