SCHEMBL20004184

SCHEMBL20004184

CC1(C)c2cc(OS(=O)C(F)(F)F)ccc2C(=O)c2c1[nH]c1ncccc21

nearest known ligand 0.50

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALK Q9UM73 20/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL897204 0.84 ALK (0.51) ALK
SCHEMBL897702 0.84 ALK (0.56) ALK
SCHEMBL897681 0.77 ALK (0.58) ALK
SCHEMBL20004183 0.76 ALK (0.68) ALK
SCHEMBL21443250 0.68 ALK (0.60) ALK
SCHEMBL30010107 0.68 ALK (0.53) ALK
SCHEMBL898538 0.67 ALK (0.55) ALK
SCHEMBL29962723 0.67 ALK (0.55) ALK
SCHEMBL897805 0.67 ALK (0.52) ALK
SCHEMBL897599 0.66 ALK (0.56) ALK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2975024-B1 TETRACYCLIC COMPOUNDS CHUGAI PHARMACEUTICAL CO LTD (JP) 2018-03-28 EP disclosed