Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.71 |
| ▸ | EML4 | Q9HC35 | 2/20 | 0.71 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.71 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.71 |
| ▸ | KDR | P35968 | 2/20 | 0.68 |
| ▸ | INSR | P06213 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20004209 | 0.91 | ALK (0.73) | ALKEML4SRPK2SRPK1KDR | |
| SCHEMBL898245 | 0.87 | ALK (0.77) | ALKEML4SRPK2SRPK1KDR | |
| SCHEMBL23593110 | 0.86 | ALK (0.86) | ALKEML4SRPK2SRPK1KDR | |
| SCHEMBL898370 | 0.85 | ALK (0.78) | ALKEML4SRPK2SRPK1KDR | |
| SCHEMBL10283144 | 0.85 | ALK (0.78) | ALKEML4SRPK2SRPK1KDR | |
| SCHEMBL29963163 | 0.85 | ALK (0.78) | ALKEML4SRPK2SRPK1KDR | |
| SCHEMBL29961870 | 0.85 | ALK (0.78) | ALKEML4SRPK2SRPK1KDR | |
| SCHEMBL898278 | 0.84 | ALK (1.00) | ALKEML4SRPK2SRPK1KDR | |
| SCHEMBL29962440 | 0.84 | ALK (1.00) | ALKEML4SRPK2SRPK1KDR | |
| SCHEMBL897797 | 0.84 | ALK (0.75) | ALKEML4SRPK2SRPK1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |