Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.49 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10283676 | 0.90 | ALK (0.53) | ALKEML4KDR | |
| SCHEMBL7810856 | 0.88 | ALK (0.49) | ALKEML4 | |
| SCHEMBL897751 | 0.87 | ALK (0.66) | ALKEML4KDR | |
| SCHEMBL897242 | 0.79 | ALK (0.76) | ALKEML4 | |
| SCHEMBL7815455 | 0.77 | ALK (0.52) | ALKEML4 | |
| SCHEMBL897420 | 0.76 | ALK (0.67) | ALKEML4 | |
| SCHEMBL24676161 | 0.75 | ALK (0.49) | ALKEML4 | |
| SCHEMBL20004233 | 0.74 | ALK (0.64) | ALKEML4KDR | |
| SCHEMBL20366523 | 0.73 | ALK (0.63) | ALKEML4KDR | |
| SCHEMBL20004663 | 0.71 | ALK (0.75) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |