SCHEMBL20004260

SCHEMBL20004260

Cn1c2c(c3ccc(Br)cc31)C(=O)c1ccc(OCC(O)CCO)cc1C2(C)C

nearest known ligand 0.71

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALK Q9UM73 20/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21443207 1.00 ALK (0.71) ALK
SCHEMBL898330 0.93 ALK (0.82) ALK
SCHEMBL898332 0.93 ALK (0.82) ALK
SCHEMBL898333 0.93 ALK (0.82) ALK
SCHEMBL1756013 0.90 ALK (0.77) ALK
SCHEMBL898272 0.89 ALK (0.67) ALK
SCHEMBL20366646 0.88 ALK (0.84) ALK
SCHEMBL20004294 0.88 ALK (0.84) ALK
SCHEMBL20004258 0.87 ALK (0.68) ALK
SCHEMBL20004281 0.86 ALK (0.62) ALK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2975024-B1 TETRACYCLIC COMPOUNDS CHUGAI PHARMACEUTICAL CO LTD (JP) 2018-03-28 EP disclosed