Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 17/20 | 0.56 |
| ▸ | SRPK1 | Q96SB4 | 4/20 | 0.52 |
| ▸ | SRPK2 | P78362 | 3/20 | 0.52 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL897212 | 0.84 | ALK (0.66) | ALKSRPK1SRPK2EML4 | |
| SCHEMBL16775678 | 0.81 | ALK (0.66) | ALKSRPK1SRPK2EML4 | |
| SCHEMBL29895705 | 0.80 | ALK (0.73) | ALKSRPK1SRPK2EML4 | |
| SCHEMBL897360 | 0.80 | ALK (0.65) | ALKSRPK1SRPK2EML4 | |
| SCHEMBL897343 | 0.80 | ALK (0.73) | ALKSRPK1SRPK2EML4 | |
| SCHEMBL897572 | 0.79 | SRPK1 (0.72) | ALKSRPK1SRPK2EML4 | |
| SCHEMBL20004657 | 0.78 | ALK (0.63) | ALKSRPK1SRPK2EML4 | |
| SCHEMBL1755862 | 0.78 | ALK (0.63) | ALKSRPK1SRPK2EML4 | |
| SCHEMBL897066 | 0.78 | ALK (0.66) | ALKSRPK1SRPK2 | |
| SCHEMBL897264 | 0.78 | ALK (0.70) | ALKSRPK1SRPK2EML4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |