Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.71 |
| ▸ | KIT | P10721 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21443155 | 1.00 | ALK (0.71) | ALKKITKDR | |
| SCHEMBL897974 | 0.83 | ALK (1.00) | ALKKITKDR | |
| SCHEMBL20366616 | 0.83 | ALK (0.51) | ALKKITKDR | |
| SCHEMBL21443235 | 0.79 | ALK (0.43) | ALK | |
| SCHEMBL20004774 | 0.79 | ALK (0.43) | ALK | |
| SCHEMBL21443270 | 0.75 | ALK (0.70) | ALKKITKDR | |
| SCHEMBL7805433 | 0.75 | ALK (0.75) | ALKKITKDR | |
| SCHEMBL21766995 | 0.75 | ALK (0.44) | ALK | |
| SCHEMBL896351 | 0.73 | ALK (1.00) | ALKKITKDR | |
| SCHEMBL20366644 | 0.71 | ALK (0.61) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |