Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20004836 | 0.88 | ALK (0.47) | ALK | |
| SCHEMBL897933 | 0.86 | ALK (0.56) | ALK | |
| SCHEMBL897932 | 0.86 | ALK (0.56) | ALK | |
| SCHEMBL897934 | 0.86 | ALK (0.56) | ALK | |
| SCHEMBL20356892 | 0.84 | ALK (0.51) | ALK | |
| SCHEMBL898089 | 0.80 | ALK (0.50) | ALK | |
| SCHEMBL898095 | 0.79 | ALK (0.47) | ALK | |
| SCHEMBL898094 | 0.79 | ALK (0.47) | ALK | |
| SCHEMBL20004358 | 0.78 | ALK (0.75) | ALK | |
| SCHEMBL18255528 | 0.74 | ALK (0.61) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613729-A1 | TETRACYCLIC COMPOUNDS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2020-02-26 | — | — | EP | disclosed |
| EP-3345903-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2019-10-09 | — | — | EP | disclosed |
| EP-3345903-A1 | TETRACYCLIC COMPOUNDS | Chugai Seiyaku Kabushiki Kaisha (JP) | 2018-07-11 | — | — | EP | disclosed |
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |