Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 19/20 | 0.70 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.52 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.52 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29962694 | 0.88 | ALK (0.74) | ALK | |
| SCHEMBL898373 | 0.88 | ALK (0.74) | ALK | |
| SCHEMBL29962169 | 0.87 | ALK (0.77) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL898223 | 0.87 | ALK (0.77) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL18245231 | 0.87 | ALK (0.70) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL897611 | 0.84 | ALK (0.81) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL897430 | 0.83 | ALK (0.82) | ALK | |
| SCHEMBL897320 | 0.82 | ALK (1.00) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL29962735 | 0.82 | ALK (1.00) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL20366684 | 0.82 | ALK (0.67) | ALKSRPK2SRPK1EML4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |