Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | AGXT | P21549 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 11/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28344411 | 0.71 | IDO1 (0.69) | IDO1AGXTMAOBMAOAHCAR2 | |
| SCHEMBL13676864 | 0.70 | IDO1 (0.55) | IDO1AGXTMAOBMAOASCN9A | |
| SCHEMBL360528 | 0.69 | NR4A2 (0.55) | IDO1AGXTMAOBMAOAHCAR2 | |
| SCHEMBL16018344 | 0.68 | IDO1 (0.60) | IDO1AGXTMAOBHCAR2 | |
| SCHEMBL10294624 | 0.68 | IDO1 (0.60) | IDO1AGXTMAOBMAOAHCAR2 | |
| SCHEMBL22537516 | 0.67 | IDO1 (0.50) | IDO1AGXTMAOBMAOASCN9A | |
| SCHEMBL20004351 | 0.67 | IDO1 (0.50) | IDO1AGXTMAOBMAOASCN9A | |
| SCHEMBL21518127 | 0.67 | IDO1 (0.58) | IDO1AGXTMAOBMAOAHCAR2 | |
| SCHEMBL10314838 | 0.67 | IDO1 (0.58) | IDO1AGXTMAOBMAOAHCAR2 | |
| SCHEMBL3254928 | 0.67 | MAOB (0.51) | IDO1AGXTMAOBMAOAHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515912-B1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NAT RECH SCIENT (FR) | 2020-10-14 | — | — | EP | disclosed |
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |