SCHEMBL20004388

SCHEMBL20004388

CCN(CC)CCCc1ccc2c(c1)C(C)(C)c1c(c3ccc(C)cc3n1C)C2=O

nearest known ligand 0.70

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALK Q9UM73 19/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL898596 0.82 ALK (1.00) ALK
SCHEMBL29962888 0.82 ALK (1.00) ALK
SCHEMBL898156 0.72 ALK (0.82) ALK
SCHEMBL29962744 0.70 ALK (0.81) ALK
SCHEMBL897188 0.70 ALK (0.81) ALK
SCHEMBL20366459 0.69 ALK (0.53) ALK
SCHEMBL20366520 0.68 ALK (0.77) ALK
SCHEMBL1703626 0.67 ALK (0.59) ALK
SCHEMBL18252768 0.67 ALK (0.74) ALK
SCHEMBL24676302 0.65 ALK (0.64) ALK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2975024-B1 TETRACYCLIC COMPOUNDS CHUGAI PHARMACEUTICAL CO LTD (JP) 2018-03-28 EP disclosed