Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.87 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20356879 | 1.00 | ALK (0.87) | ALK | |
| SCHEMBL17448453 | 1.00 | ALK (0.87) | ALK | |
| SCHEMBL897771 | 1.00 | ALK (0.87) | ALK | |
| SCHEMBL897163 | 0.93 | ALK (0.85) | ALK | |
| SCHEMBL29962392 | 0.93 | ALK (1.00) | ALK | |
| SCHEMBL897570 | 0.93 | ALK (1.00) | ALK | |
| SCHEMBL896662 | 0.92 | ALK (0.87) | ALK | |
| SCHEMBL896663 | 0.92 | ALK (0.87) | ALK | |
| SCHEMBL896660 | 0.92 | ALK (0.87) | ALK | |
| SCHEMBL20004321 | 0.89 | ALK (0.81) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613729-A1 | TETRACYCLIC COMPOUNDS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2020-02-26 | — | — | EP | disclosed |
| EP-3345903-A1 | TETRACYCLIC COMPOUNDS | Chugai Seiyaku Kabushiki Kaisha (JP) | 2018-07-11 | — | — | EP | disclosed |
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |