Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 19/20 | 0.72 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.55 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.55 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7806692 | 0.90 | ALK (0.72) | ALKSRPK2SRPK1 | |
| SCHEMBL21443157 | 0.89 | ALK (0.64) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL16775671 | 0.88 | ALK (0.78) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL897185 | 0.86 | ALK (0.79) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL10283126 | 0.86 | ALK (0.78) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL897528 | 0.86 | ALK (0.92) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL898201 | 0.85 | ALK (0.76) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL897269 | 0.85 | ALK (0.76) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL897244 | 0.85 | ALK (0.72) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL897390 | 0.84 | ALK (0.77) | ALKSRPK2SRPK1EML4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345903-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2019-10-09 | — | — | EP | disclosed |
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |