Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.59 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811393 | 0.90 | ALK (0.61) | ALKEML4KDRKIT | |
| SCHEMBL24676750 | 0.85 | ALK (0.74) | ALKEML4KDR | |
| SCHEMBL897687 | 0.83 | ALK (0.84) | ALKEML4KDRKIT | |
| SCHEMBL21443254 | 0.79 | ALK (0.73) | ALKEML4KDR | |
| SCHEMBL21443256 | 0.79 | ALK (0.73) | ALKEML4KDR | |
| SCHEMBL7810161 | 0.79 | ALK (0.68) | ALKEML4KDR | |
| SCHEMBL20004239 | 0.79 | ALK (0.60) | ALKKDRKIT | |
| SCHEMBL7816274 | 0.78 | ALK (0.59) | ALKEML4KDRKIT | |
| SCHEMBL28913325 | 0.78 | ALK (0.59) | ALKEML4KDRKIT | |
| SCHEMBL20004124 | 0.78 | ALK (0.56) | ALKEML4KDRKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |