Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.88 |
| ▸ | KDR | P35968 | 5/20 | 0.74 |
| ▸ | KIT | P10721 | 4/20 | 0.74 |
| ▸ | INSR | P06213 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL897049 | 0.95 | ALK (0.87) | ALKKDRKITINSR | |
| SCHEMBL897243 | 0.94 | ALK (1.00) | ALKKDRKITINSR | |
| Hydrochloric Acid SCHEMBL14990717 | 0.93 | ALK (0.98) | ALKKDRKITINSR | |
| Hydrochloric Acid SCHEMBL30730873 | 0.93 | ALK (0.98) | ALKKDRKITINSR | |
| SCHEMBL897175 | 0.91 | ALK (0.94) | ALKKDRKITINSR | |
| SCHEMBL896869 | 0.90 | ALK (1.00) | ALKKDRKITINSR | |
| SCHEMBL29895699 | 0.89 | ALK (0.84) | ALKKDRKIT | |
| SCHEMBL29895704 | 0.89 | ALK (0.84) | ALKKDRKIT | |
| SCHEMBL897896 | 0.89 | ALK (0.84) | ALKKDRKIT | |
| SCHEMBL29895703 | 0.89 | ALK (0.84) | ALKKDRKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |