Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.66 |
| ▸ | KDR | P35968 | 4/20 | 0.53 |
| ▸ | KIT | P10721 | 2/20 | 0.51 |
| ▸ | EML4 | Q9HC35 | 2/20 | 0.50 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.49 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL897357 | 0.87 | ALK (0.80) | ALKKDRKITEML4SRPK2 | |
| SCHEMBL1755877 | 0.86 | ALK (0.62) | ALKKDRKITEML4SRPK2 | |
| SCHEMBL896899 | 0.80 | ALK (1.00) | ALKKDRKIT | |
| Hydrochloric Acid SCHEMBL14990947 | 0.79 | ALK (0.98) | ALKKDRKIT | |
| Hydrochloric Acid SCHEMBL30730875 | 0.79 | ALK (0.98) | ALKKDRKIT | |
| SCHEMBL897176 | 0.78 | ALK (0.78) | ALKKDRKITEML4SRPK2 | |
| SCHEMBL7815503 | 0.78 | ALK (0.78) | ALKKDRKIT | |
| SCHEMBL10283152 | 0.77 | ALK (0.83) | ALKKDRKIT | |
| SCHEMBL1703861 | 0.76 | ALK (0.77) | ALKKDRKITEML4SRPK2 | |
| SCHEMBL897857 | 0.75 | ALK (0.85) | ALKKDRKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |