Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.80 |
| ▸ | KDR | P35968 | 3/20 | 0.80 |
| ▸ | KIT | P10721 | 2/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL897475 | 0.95 | ALK (0.87) | ALKKDRKIT | |
| SCHEMBL897359 | 0.93 | ALK (0.83) | ALKKDRKIT | |
| SCHEMBL897985 | 0.92 | ALK (0.81) | ALKKDRKIT | |
| SCHEMBL29962399 | 0.92 | ALK (0.81) | ALKKDRKIT | |
| SCHEMBL897178 | 0.90 | ALK (0.87) | ALKKDRKIT | |
| SCHEMBL897307 | 0.89 | ALK (1.00) | ALKKDRKIT | |
| SCHEMBL897664 | 0.88 | ALK (1.00) | ALKKDRKIT | |
| SCHEMBL897222 | 0.88 | ALK (1.00) | ALKKDRKIT | |
| Hydrochloric Acid SCHEMBL31236828 | 0.87 | ALK (0.98) | ALKKDRKIT | |
| SCHEMBL897270 | 0.87 | ALK (1.00) | ALKKDRKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |