Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.72 |
| ▸ | KDR | P35968 | 5/20 | 0.61 |
| ▸ | KIT | P10721 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL898372 | 0.91 | ALK (0.86) | ALKKDRKIT | |
| SCHEMBL29962650 | 0.91 | ALK (0.86) | ALKKDRKIT | |
| SCHEMBL30389803 | 0.84 | ALK (1.00) | ALKKDRKIT | |
| SCHEMBL898337 | 0.84 | ALK (1.00) | ALKKDRKIT | |
| SCHEMBL22369325 | 0.82 | ALK (0.72) | ALKKDRKIT | |
| SCHEMBL22369405 | 0.81 | ALK (0.84) | ALKKDR | |
| SCHEMBL898396 | 0.81 | ALK (0.85) | ALKKDRKIT | |
| SCHEMBL22369381 | 0.79 | ALK (0.75) | ALKKDRKIT | |
| SCHEMBL897359 | 0.78 | ALK (0.83) | ALKKDRKIT | |
| SCHEMBL897775 | 0.78 | ALK (0.80) | ALKKDRKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |