Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 19/20 | 0.63 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL897808 | 0.88 | ALK (0.81) | ALK | |
| SCHEMBL29962074 | 0.88 | ALK (0.81) | ALK | |
| SCHEMBL898667 | 0.79 | ALK (0.86) | ALK | |
| SCHEMBL29962490 | 0.79 | ALK (0.86) | ALK | |
| SCHEMBL29962179 | 0.77 | ALK (1.00) | ALK | |
| SCHEMBL897835 | 0.77 | ALK (1.00) | ALK | |
| SCHEMBL897142 | 0.76 | ALK (0.87) | ALK | |
| SCHEMBL29962167 | 0.76 | ALK (0.87) | ALK | |
| SCHEMBL29962744 | 0.74 | ALK (0.81) | ALK | |
| SCHEMBL897188 | 0.74 | ALK (0.81) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |