Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.45 |
| ▸ | EML4 | Q9HC35 | 4/20 | 0.45 |
| ▸ | SRPK1 | Q96SB4 | 3/20 | 0.45 |
| ▸ | SRPK2 | P78362 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL898387 | 0.84 | ALK (0.64) | ALKEML4SRPK1SRPK2KDR | |
| SCHEMBL21443260 | 0.77 | ALK (0.71) | ALKEML4SRPK1SRPK2KDR | |
| SCHEMBL29962511 | 0.77 | ALK (0.67) | ALKEML4SRPK1SRPK2KDR | |
| SCHEMBL24676288 | 0.77 | ALK (0.61) | ALKEML4SRPK1SRPK2KDR | |
| SCHEMBL21443254 | 0.75 | ALK (0.73) | ALKEML4SRPK1SRPK2KDR | |
| SCHEMBL24676891 | 0.74 | ALK (0.55) | ALKEML4SRPK1SRPK2KDR | |
| SCHEMBL21443256 | 0.73 | ALK (0.73) | ALKEML4SRPK1SRPK2KDR | |
| SCHEMBL24675806 | 0.73 | ALK (0.59) | ALKEML4SRPK1SRPK2KDR | |
| SCHEMBL24676750 | 0.72 | ALK (0.74) | ALKEML4SRPK1SRPK2KDR | |
| SCHEMBL29292096 | 0.72 | ALK (0.74) | ALKEML4SRPK1SRPK2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |