Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.36 |
| ▸ | RARB | P10826 | 5/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MPL | P40238 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19999588 | 0.93 | RARB (0.41) | HRH3RARBRARARARGTSHR | |
| SCHEMBL20006711 | 0.93 | HRH3 (0.36) | HRH3RARBRARARARGTSHR | |
| SCHEMBL20004902 | 0.92 | RARB (0.37) | HRH3RARBRARARARGTSHR | |
| SCHEMBL19999495 | 0.92 | RARB (0.37) | HRH3RARBRARARARGTSHR | |
| SCHEMBL20004889 | 0.92 | RARB (0.39) | HRH3RARBRARARARGTSHR | |
| SCHEMBL19999623 | 0.89 | RARB (0.38) | HRH3RARBRARARARGTSHR | |
| SCHEMBL20005244 | 0.89 | RARB (0.40) | HRH3RARBRARARARGTSHR | |
| SCHEMBL20004905 | 0.87 | ESR1 (0.34) | — | |
| SCHEMBL19999489 | 0.87 | ACACB (0.40) | RARBRARATSHRHSD17B10MAPK1 | |
| SCHEMBL19999492 | 0.86 | TSHR (0.44) | HRH3RARBRARARARGTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299439-A1 | LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC Corporation (JP) | 2018-03-28 | — | — | EP | disclosed |