SCHEMBL20004977

SCHEMBL20004977

CC1(C)c2cc(OCCCN=O)ccc2C(=O)c2c1oc1cc(F)ccc21

nearest known ligand 0.73

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALK Q9UM73 20/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20004570 0.89 ALK (0.73) ALK
SCHEMBL20004566 0.89 ALK (0.59) ALK
SCHEMBL20366780 0.89 ALK (0.75) ALK
SCHEMBL1703148 0.84 ALK (1.00) ALK
SCHEMBL17448572 0.84 ALK (0.66) ALK
SCHEMBL897786 0.83 ALK (0.69) ALK
SCHEMBL24676523 0.82 ALK (0.68) ALK
SCHEMBL21443173 0.81 ALK (0.65) ALK
SCHEMBL898821 0.80 ALK (0.80) ALK
SCHEMBL24675783 0.80 ALK (0.84) ALK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2975024-B1 TETRACYCLIC COMPOUNDS CHUGAI PHARMACEUTICAL CO LTD (JP) 2018-03-28 EP disclosed