Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.50 |
| ▸ | TACR1 | P25103 | 2/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7892498 | 0.82 | IDO1 (0.69) | IDO1TACR1TSHRCYP1A2CYP2D6 | |
| SCHEMBL22537583 | 0.82 | IDO1 (0.51) | IDO1TACR1MRGPRX4TSHRNFE2L2 | |
| SCHEMBL13756779 | 0.81 | TSHR (0.62) | IDO1TACR1TSHRNFE2L2ALOX5 | |
| SCHEMBL9842310 | 0.81 | TSHR (0.62) | IDO1TACR1TSHRNFE2L2ALOX5 | |
| SCHEMBL15687841 | 0.81 | TSHR (0.62) | IDO1TACR1TSHRAPPCYP1A2 | |
| SCHEMBL20004351 | 0.81 | IDO1 (0.50) | IDO1MRGPRX4 | |
| SCHEMBL2293769 | 0.80 | IDO1 (0.68) | IDO1TSHRNFE2L2ALOX5RXRA | |
| SCHEMBL5250014 | 0.79 | APP (0.53) | IDO1TACR1MRGPRX4APPRAB9A | |
| SCHEMBL4507875 | 0.79 | APP (0.53) | IDO1TACR1MRGPRX4APPRAB9A | |
| SCHEMBL29041352 | 0.79 | TSHR (0.65) | IDO1TACR1MRGPRX4TSHRRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515912-B1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NAT RECH SCIENT (FR) | 2020-10-14 | — | — | EP | disclosed |
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |