Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21147094 | 0.90 | MAPT (0.33) | MAPTSNCA | |
| SCHEMBL20004640 | 0.86 | MAPT (0.41) | MAPTSNCAAPP | |
| SCHEMBL22537754 | 0.74 | SNCA (0.52) | MAPTSNCAAPP | |
| SCHEMBL20005141 | 0.70 | SNCA (0.63) | MAPTSNCAAPP | |
| SCHEMBL20005163 | 0.66 | MAPT (0.44) | MAPTSNCAAPP | |
| SCHEMBL22537542 | 0.63 | SNCA (0.39) | MAPTSNCA | |
| SCHEMBL22537869 | 0.63 | SNCA (0.62) | MAPTSNCAAPP | |
| SCHEMBL20004522 | 0.62 | SNCA (0.72) | MAPTSNCAAPP | |
| SCHEMBL20004443 | 0.62 | SNCA (0.60) | MAPTSNCAAPP | |
| SCHEMBL22537852 | 0.61 | MAPT (0.46) | MAPTSNCAAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515912-B1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NAT RECH SCIENT (FR) | 2020-10-14 | — | — | EP | disclosed |
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |