Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 12/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 2/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20004399 | 0.88 | SNCA (0.75) | SNCAMAPTAPPKITFGFR4 | |
| SCHEMBL22537877 | 0.86 | SNCA (0.75) | SNCAMAPTAURKAAPP | |
| SCHEMBL22537701 | 0.81 | SNCA (0.56) | SNCAMAPTKIT | |
| SCHEMBL21147095 | 0.79 | SNCA (0.57) | SNCAMAPTAPP | |
| SCHEMBL22537820 | 0.78 | SNCA (0.51) | SNCAMAPTBRD4KIT | |
| SCHEMBL20004669 | 0.78 | SNCA (0.73) | SNCAMAPTAPPKIT | |
| SCHEMBL22537673 | 0.77 | SNCA (0.55) | SNCAMAPTAPP | |
| SCHEMBL20004468 | 0.76 | SNCA (0.71) | SNCAMAPTAPP | |
| SCHEMBL20004440 | 0.76 | SNCA (0.71) | SNCAMAPTAPPKIT | |
| SCHEMBL20005159 | 0.75 | SNCA (0.69) | SNCAMAPTAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |