Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | VCP | P55072 | 2/20 | 0.31 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.30 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415356 | 0.83 | SNCA (0.39) | BRD4SNCAGRIN1GRIN2BFGFR1 | |
| SCHEMBL13204738 | 0.80 | BRD4 (0.55) | BRD4PIK3CGABL1VCP | |
| SCHEMBL13854154 | 0.79 | BRD4 (0.51) | BRD4PIK3CGGRIN1GRIN2BKIT | |
| SCHEMBL25153266 | 0.79 | BRD4 (0.50) | BRD4PIK3CGFGFR1ABL1 | |
| SCHEMBL30280433 | 0.79 | BRD4 (0.50) | BRD4PIK3CGFGFR1ABL1 | |
| SCHEMBL1772724 | 0.79 | BRD4 (0.50) | BRD4PIK3CGABL1VCP | |
| SCHEMBL5925799 | 0.77 | ABL1 (0.39) | SNCAGRIN1GRIN2BKITABL1 | |
| SCHEMBL2038785 | 0.76 | BRD4 (0.47) | BRD4SNCAPIK3CGKITAGBL2 | |
| SCHEMBL1101219 | 0.74 | GPR17 (0.38) | SNCAABL1AGBL2 | |
| SCHEMBL12655295 | 0.73 | BRD4 (0.44) | BRD4PIK3CGVCPNR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |