Deoxyinosine

Deoxyinosine

SCHEMBL2000526

OC[C@H]1O[C@@H](n2cnc3c(O)ncnc32)C[C@@H]1O.OC[C@H]1O[C@@H](n2cnc3c(O)ncnc32)C[C@@H]1O

nearest known ligand 0.73

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Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.73
PNP P00491 1/20 0.58
LMNA P02545 1/20 0.58
TP53 P04637 1/20 0.58
HTT P42858 1/20 0.58
PDE4D Q08499 1/20 0.58
PDE3A Q14432 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
RXFP1 Q9HBX9 1/20 0.58
PIM1 P11309 1/20 0.58
CSNK2A2 P19784 1/20 0.58
CSNK2B P67870 1/20 0.58
CSNK2A1 P68400 1/20 0.58
CSNK2A3 Q8NEV1 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Deoxyinosine SCHEMBL324457 1.00 HIF1A (0.73) HIF1APNPLMNATP53HTT
Deoxyinosine SCHEMBL5982293 1.00 HIF1A (0.73) HIF1APNPLMNATP53HTT
Deoxyinosine SCHEMBL24307 1.00 HIF1A (0.73) HIF1APNPLMNATP53HTT
Deoxyinosine SCHEMBL7191121 1.00 HIF1A (0.73) HIF1APNPLMNATP53HTT
Deoxyinosine SCHEMBL5684889 0.94 HIF1A (0.66) HIF1APNPLMNATP53HTT
Deoxyinosine SCHEMBL1401252 0.94 HIF1A (0.66) HIF1APNPLMNATP53HTT
Deoxyadenosine SCHEMBL8581593 0.93 HIF1A (0.65) HIF1APNPLMNATP53HTT
Deoxyinosine SCHEMBL28172526 0.92 HIF1A (0.64) HIF1APNPLMNATP53HTT
Deoxyadenosine SCHEMBL18062490 0.91 SMN1; SMN2 (0.64) HIF1APNPLMNATP53HTT
Inosine SCHEMBL8648208 0.91 HIF1A (0.62) HIF1ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105861743-A Internal standard-containing kit and detection method for detecting hepatitis C virus nucleic acid 珠海丽珠试剂股份有限公司 2016-08-17 CN disclosed
US-7960159-B2 Detection of nucleic acid differences using combined endonuclease cleavage and ligation reactions Corneil Research Foundation, Inc. (US) 2011-06-14 US disclosed
US-20100323425-A1 DETECTION OF NUCLEIC ACID DIFFERENCES USING COMBINED ENDONUCLEASE CLEAVAGE AND LIGATION REACTIONS CORNELL RESEARCH FOUNDATION, INC. (US) 2010-12-23 US disclosed
US-7807431-B2 Detection of nucleic acid differences using combined endonuclease cleavage and ligation reactions CORNELL RESEARCH FOUNDATION, INC. (US) 2010-10-05 US disclosed
EP-1343869-B1 DETECTION OF NUCLEIC ACID DIFFERENCES USING COMBINED ENDONUCLEASE CLEAVAGE AND LIGATION REACTIONS CORNELL RES FOUNDATION INC (US) 2009-01-28 EP disclosed
US-20080003601-A1 DETECTION OF NUCLEIC ACID DIFFERENCES USING COMBINED ENDONUCLEASE CLEAVAGE AND LIGATION REACTIONS CORNELL RESEARCH FOUNDATION, INC. (US) 2008-01-03 US disclosed
US-7198894-B2 Detection of nucleic acid differences using combined endonuclease cleavage and ligation reactions CORNELL RESEARCH FOUNDATION, INC. (US) 2007-04-03 US disclosed
EP-1343869-A4 DETECTION OF NUCLEIC ACID DIFFERENCES USING COMBINED ENDONUCLEASE CLEAVAGE AND LIGATION REACTIONS CORNELL RES FOUNDATION INC (US) 2005-06-01 EP disclosed
EP-1343869-A2 DETECTION OF NUCLEIC ACID DIFFERENCES USING COMBINED ENDONUCLEASE CLEAVAGE AND LIGATION REACTIONS CORNELL RESEARCH FOUNDATION, INC. (US) 2003-09-17 EP disclosed
US-20030148283-A1 Detection of nucleic acid differences using combined endonuclease cleavage and ligation reactions NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-08-07 US disclosed
WO-2002044335-A2 DETECTION OF NUCLEIC ACID DIFFERENCES USING COMBINED ENDONUCLEASE CLEAVAGE AND LIGATION REACTIONS CORNELL RESEARCH FOUNDATION, INC. (US) 2002-06-06 WO disclosed