Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10144798 | 1.00 | CHRM2 (0.40) | CHRM2CHRM1CHRM3HSD17B10NR1H2 | |
| SCHEMBL26791171 | 0.88 | NR1H2 (0.42) | CHRM2CHRM1CHRM3HSD17B10NR1H2 | |
| SCHEMBL12660832 | 0.88 | NR1H2 (0.42) | CHRM2CHRM1CHRM3HSD17B10NR1H2 | |
| SCHEMBL1914221 | 0.88 | NR1H2 (0.42) | CHRM2CHRM1CHRM3HSD17B10NR1H2 | |
| SCHEMBL116548 | 0.88 | NR1H2 (0.42) | CHRM2CHRM1CHRM3HSD17B10NR1H2 | |
| SCHEMBL19557223 | 0.88 | NR1H2 (0.42) | CHRM2CHRM1CHRM3HSD17B10NR1H2 | |
| SCHEMBL116141 | 0.88 | NR1H2 (0.42) | CHRM2CHRM1CHRM3HSD17B10NR1H2 | |
| SCHEMBL1914633 | 0.88 | NR1H2 (0.42) | CHRM2CHRM1CHRM3HSD17B10NR1H2 | |
| SCHEMBL10145374 | 0.87 | CHRM2 (0.39) | CHRM2CHRM1CHRM3HSD17B10NR1H2 | |
| SCHEMBL17980096 | 0.85 | HSD17B10 (0.41) | CHRM2CHRM1CHRM3HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021213353-A1 | AMIDE OR SULFONAMIDE DERIVATIVE AND USE THEREOF | 苏州恩华生物医药科技有限公司 (CN) | 2021-10-28 | — | — | WO | disclosed |
| WO-2018056854-A1 | BLOOD-BRAIN BARRIER-PENETRANT DOPAMINE-B-HYDROXYLASE INHIBITORS | BIAL - PORTELA & Cª, S.A. (PT) | 2018-03-29 | — | — | WO | disclosed |