Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24992417 | 0.76 | — | — | |
| SCHEMBL1755367 | 0.68 | GRIN2D (0.36) | KDM1AMAOAMAOB | |
| SCHEMBL5221830 | 0.66 | — | — | |
| SCHEMBL24992265 | 0.65 | GRIN2D (0.31) | — | |
| Hydrochloric Acid SCHEMBL20721240 | 0.64 | — | — | |
| SCHEMBL24608195 | 0.64 | SPHK1 (0.31) | — | |
| SCHEMBL284624 | 0.62 | — | — | |
| SCHEMBL5224599 | 0.62 | — | — | |
| SCHEMBL17427767 | 0.61 | TDP1 (0.35) | — | |
| SCHEMBL19425718 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2940019-B1 | SUBSTITUTED SPIROPYRIDO[1,2-a]PYRAZINE DERIVATIVE AND MEDICINAL USE THEREOF AS HIV INTEGRASE INHIBITOR | JAPAN TOBACCO INC (JP) | 2018-03-28 | — | — | EP | disclosed |