Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 6/20 | 0.31 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | FDPS | P14324 | 8/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21233371 | 0.86 | TSHR (0.33) | GGPS1CNR2FDPS | |
| SCHEMBL26742610 | 0.86 | TSHR (0.33) | GGPS1CNR2FDPS | |
| SCHEMBL21784193 | 0.86 | TSHR (0.33) | GGPS1CNR2FDPS | |
| SCHEMBL26742748 | 0.86 | TSHR (0.33) | GGPS1CNR2FDPS | |
| SCHEMBL23456878 | 0.86 | TSHR (0.33) | GGPS1CNR2FDPS | |
| SCHEMBL26456152 | 0.81 | CNR2 (0.30) | CNR1CNR2 | |
| SCHEMBL18862706 | 0.80 | HRH2 (0.32) | CNR1CNR2 | |
| SCHEMBL26742323 | 0.79 | CNR2 (0.34) | GGPS1CNR1CNR2FDPS | |
| SCHEMBL25101423 | 0.77 | — | — | |
| SCHEMBL22951340 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10519125-B2 | Flavagline derivatives | PIERRE FABRE MEDICAMENT (FR) | 2019-12-31 | — | — | US | disclosed |
| US-20180086729-A1 | FLAVAGLINE DERIVATIVES | PIERRE FABRE MEDICAMENT (FR) | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086729-A1 | FLAVAGLINE DERIVATIVES | GCG, GCGR, KRAS | GGPS1 702/4885CNR1 1435/4885CNR2 1295/4885 |
| US-10519125-B2 | Flavagline derivatives | GCG, GCGR, KRAS | GGPS1 702/4885CNR1 1435/4885CNR2 1295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.