⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22520932 | 0.81 | — | — | |
| SCHEMBL21471628 | 0.75 | — | — | |
| SCHEMBL19664842 | 0.70 | — | — | |
| SCHEMBL8554201 | 0.67 | — | — | |
| SCHEMBL22297362 | 0.67 | — | — | |
| SCHEMBL20992325 | 0.65 | — | — | |
| SCHEMBL15382244 | 0.65 | — | — | |
| SCHEMBL23572364 | 0.62 | — | — | |
| SCHEMBL12153789 | 0.62 | — | — | |
| SCHEMBL14865875 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299361-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL | Rhizen Pharmaceuticals S.A. (CH) | 2018-03-28 | — | — | EP | disclosed |