Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRACR2A | Q9BSW2 | 6/20 | 0.47 |
| ▸ | ABL1 | P00519 | 4/20 | 0.41 |
| ▸ | VCP | P55072 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667987 | 0.76 | CRACR2A (0.77) | CRACR2A | |
| SCHEMBL12638237 | 0.76 | CRACR2A (0.61) | CRACR2ADHODH | |
| SCHEMBL31703904 | 0.64 | TRPV1 (0.43) | CRACR2AEGFR | |
| SCHEMBL1882816 | 0.64 | CRACR2A (1.00) | CRACR2A | |
| SCHEMBL1670537 | 0.59 | CRACR2A (1.00) | CRACR2A | |
| SCHEMBL12638178 | 0.59 | CRACR2A (0.71) | CRACR2A | |
| SCHEMBL12638092 | 0.58 | CRACR2A (0.85) | CRACR2A | |
| SCHEMBL12638111 | 0.58 | CRACR2A (0.60) | CRACR2A | |
| SCHEMBL1881673 | 0.57 | CRACR2A (0.78) | CRACR2A | |
| SCHEMBL1884926 | 0.57 | CRACR2A (1.00) | CRACR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299361-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL | Rhizen Pharmaceuticals S.A. (CH) | 2018-03-28 | — | — | EP | disclosed |