Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 19/20 | 0.75 |
| ▸ | ATM | Q13315 | 19/20 | 0.75 |
| ▸ | PIK3CA | P42336 | 15/20 | 0.75 |
| ▸ | ATR | Q13535 | 7/20 | 0.75 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20006507 | 0.92 | ATM (0.84) | MTORATMPIK3CAATRKCNH2 | |
| SCHEMBL17272510 | 0.86 | MTOR (1.00) | MTORATMPIK3CAATRKCNH2 | |
| SCHEMBL17246658 | 0.86 | MTOR (1.00) | MTORATMPIK3CAATRKCNH2 | |
| SCHEMBL17242486 | 0.86 | ATM (1.00) | MTORATMPIK3CAATRKCNH2 | |
| SCHEMBL17245494 | 0.86 | ATM (1.00) | MTORATMPIK3CAATRKCNH2 | |
| SCHEMBL17242644 | 0.86 | ATM (1.00) | MTORATMPIK3CAATRKCNH2 | |
| SCHEMBL20006120 | 0.86 | MTOR (1.00) | MTORATMPIK3CAATRKCNH2 | |
| SCHEMBL20006498 | 0.86 | ATM (1.00) | MTORATMPIK3CAATRKCNH2 | |
| SCHEMBL17241780 | 0.86 | ATM (1.00) | MTORATMPIK3CAATRKCNH2 | |
| SCHEMBL17246359 | 0.86 | ATM (1.00) | MTORATMPIK3CAATRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3140303-B1 | IMIDAZO[4,5-C]QUINOLIN-2-ONE COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2018-03-28 | — | — | EP | disclosed |