SCHEMBL20006923

SCHEMBL20006923

Cc1cc(OC(F)(F)c2c(F)cccc2F)cc(F)c1C#Cc1ccc(-c2ccc(-c3cc(F)c(F)c(F)c3)c(F)c2)c(F)c1

nearest known ligand 0.30

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.30
AKR1C2 P52895 1/20 0.30
GRM5 P41594 1/20 0.30
ALOX5AP P20292 1/20 0.30
FEN1 P39748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20006683 0.98 GRM5 (0.31) GRM5
SCHEMBL20006717 0.87 TNKS (0.30)
SCHEMBL20005249 0.86
SCHEMBL19999567 0.85 RARB (0.32)
SCHEMBL20006838 0.83 TNKS (0.30)
SCHEMBL19999633 0.83 GRM2 (0.30)
SCHEMBL19999470 0.83 RARB (0.32)
SCHEMBL19999507 0.82 ALOX5AP (0.31) ALOX5APFEN1
SCHEMBL19999443 0.82 ALOX5AP (0.31) ALOX5APFEN1
SCHEMBL20006839 0.82 ERN1 (0.36) ALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10208249-B2 Liquid crystal compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2019-02-19 US disclosed
US-20180086979-A1 LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-03-29 US disclosed