Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.70 |
| ▸ | CA2 | P00918 | 3/20 | 0.70 |
| ▸ | NPC1 | O15118 | 6/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.59 |
| ▸ | TUBB | P07437 | 1/20 | 0.59 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.59 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.59 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.59 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17237334 | 0.91 | POLB (0.76) | CA1CA2NPC1RAB9AMAPT | |
| SCHEMBL17236831 | 0.91 | POLB (0.62) | CA1CA2NPC1RAB9AMAPT | |
| SCHEMBL17236826 | 0.91 | POLB (0.62) | CA1CA2NPC1RAB9AMAPT | |
| SCHEMBL17237331 | 0.91 | POLB (0.76) | CA1CA2NPC1RAB9AMAPT | |
| SCHEMBL17236928 | 0.91 | POLB (0.75) | MAPTGAAPOLBALDH1A1MEN1 | |
| SCHEMBL17236926 | 0.91 | POLB (0.75) | MAPTGAAPOLBALDH1A1MEN1 | |
| SCHEMBL17237299 | 0.90 | KRAS (0.70) | CA1CA2NPC1RAB9AMAPT | |
| SCHEMBL17236695 | 0.90 | KRAS (0.70) | CA1CA2NPC1RAB9AMAPT | |
| SCHEMBL17236698 | 0.90 | KRAS (0.70) | CA1CA2NPC1RAB9AMAPT | |
| SCHEMBL17236982 | 0.90 | NPC1 (0.63) | CA1CA2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2942345-B1 | 3,4,5-TRIMETHOXYSTYRYLARYLAMINOPROPENONES FOR THE TREATMENT OF CANCER | COUNCIL SCIENT IND RES (IN) | 2018-03-28 | — | — | EP | disclosed |