Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.51 |
| ▸ | KRAS | P01116 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.48 |
| ▸ | TUBB | P07437 | 2/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20007394 | 0.93 | MEN1 (0.56) | MEN1KMT2ACA1CA2ABCG2 | |
| SCHEMBL17237306 | 0.91 | MEN1 (0.66) | MEN1KMT2AABCG2ABCB1ALDH1A1 | |
| SCHEMBL17237310 | 0.91 | MEN1 (0.66) | MEN1KMT2AABCG2ABCB1ALDH1A1 | |
| SCHEMBL17251595 | 0.90 | CA1 (0.67) | MEN1KMT2ACA1CA2ABCG2 | |
| SCHEMBL17236830 | 0.90 | ABCG2 (0.60) | MEN1KMT2AABCG2ABCB1KRAS | |
| SCHEMBL17236833 | 0.90 | ABCG2 (0.60) | MEN1KMT2AABCG2ABCB1KRAS | |
| SCHEMBL17236855 | 0.89 | TUBB1 (0.60) | MEN1KMT2ACA1CA2ABCG2 | |
| SCHEMBL17236858 | 0.89 | TUBB1 (0.60) | MEN1KMT2ACA1CA2ABCG2 | |
| SCHEMBL17237231 | 0.88 | TUBB1 (0.60) | MEN1KMT2ACA1CA2ABCG2 | |
| SCHEMBL17236892 | 0.88 | MEN1 (0.54) | MEN1KMT2ACA1CA2ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2942345-B1 | 3,4,5-TRIMETHOXYSTYRYLARYLAMINOPROPENONES FOR THE TREATMENT OF CANCER | COUNCIL SCIENT IND RES (IN) | 2018-03-28 | — | — | EP | disclosed |