Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A2 | O15244 | 16/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29775532 | 0.89 | SLC22A2 (0.62) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL21356934 | 0.89 | SLC22A2 (0.62) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL19071762 | 0.89 | SLC22A2 (0.62) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL80152 | 0.89 | SLC22A2 (0.62) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL2679233 | 0.85 | SLC22A2 (0.46) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL83098 | 0.79 | SLC22A2 (0.48) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL80958 | 0.76 | SLC22A2 (0.53) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL19071940 | 0.74 | SLC22A2 (0.62) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL30231878 | 0.74 | SLC22A2 (0.62) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL82644 | 0.74 | SLC22A2 (0.62) | SLC22A2CYP3A4TMEM97ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3045206-B1 | POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITORY ACTIVITY | VIIV HEALTHCARE CO (US) | 2018-03-28 | — | — | EP | disclosed |