Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL60530 | 0.71 | TSHR (0.33) | TSHR | |
| SCHEMBL60531 | 0.71 | TSHR (0.33) | TSHR | |
| SCHEMBL10961358 | 0.71 | TSHR (0.43) | TSHR | |
| SCHEMBL10961361 | 0.71 | TSHR (0.43) | TSHR | |
| SCHEMBL11852299 | 0.69 | TSHR (0.32) | TSHR | |
| SCHEMBL11852301 | 0.69 | TSHR (0.32) | TSHR | |
| SCHEMBL9735218 | 0.64 | — | — | |
| SCHEMBL10959663 | 0.64 | — | — | |
| SCHEMBL18368757 | 0.64 | — | — | |
| SCHEMBL13827092 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |