Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20009921 | 0.72 | — | — | |
| SCHEMBL12024798 | 0.69 | ATM (0.50) | OPRK1 | |
| SCHEMBL24385608 | 0.64 | CCR1 (0.33) | — | |
| SCHEMBL6626587 | 0.63 | SMN1; SMN2 (0.56) | OPRK1 | |
| SCHEMBL612856 | 0.63 | KDM4E (0.48) | — | |
| SCHEMBL17382227 | 0.61 | PARP1 (0.53) | — | |
| SCHEMBL9508567 | 0.61 | KDM4E (0.47) | — | |
| SCHEMBL30711736 | 0.61 | PARP1 (0.53) | — | |
| SCHEMBL18633979 | 0.61 | KDM4E (0.33) | — | |
| SCHEMBL21886192 | 0.61 | CCR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |