⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20009893 | 1.00 | — | — | |
| SCHEMBL20008608 | 0.84 | — | — | |
| SCHEMBL20010008 | 0.71 | — | — | |
| SCHEMBL20009334 | 0.70 | — | — | |
| SCHEMBL20008475 | 0.66 | RAF1 (0.39) | — | |
| SCHEMBL20008786 | 0.64 | RAF1 (0.46) | — | |
| SCHEMBL20008890 | 0.63 | RAF1 (0.49) | — | |
| SCHEMBL20008373 | 0.63 | RAF1 (0.46) | — | |
| SCHEMBL20008216 | 0.62 | RAF1 (0.47) | — | |
| SCHEMBL20008177 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |